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-   -   Another bacteria in the gut thread (http://cellar.org/showthread.php?t=30413)

glatt 09-18-2014 08:59 AM

Another bacteria in the gut thread
 
Rather than throw this in some existing thread that isn't a good fit and that may go off on an undesirable tangent, I thought I'd start a new one.

Just read in the paper today how a new study published in Nature shows that consuming sugar substitutes instead of sugar can actually make blood sugar levels spike much more than the real sugar would have. The really interesting thing to me is that the researchers then speculated about why the results were what they were.

They theorize that the saccharin is changing the bacteria in the gut.

Quote:

In a series of experiments, researchers found that several of the most widely used types of non-calorie sweeteners in food and drinks — saccharin, sucra*lose and aspartame — caused mice to experience increased risk of glucose intolerance, a condition that can lead to diabetes.

“We are talking about very dramatic increases,” said one of the study’s co-authors, Eran Segal, a computational biologist at the Weizmann Institute of Science in Israel.

The same scientists also monitored what happened to seven human volunteers who did not typically use artificial sweeteners but were given regular doses of saccharin over the course of a week. Four developed significant glucose intolerance. Separately, the researchers analyzed nearly 400 people and found that the gut bacteria of those who used artificial sweeteners were noticeably different from people who did not.
It seems like everywhere we turn, there is new evidence coming out that problems with bacteria in the gut are causing a wide range diseases.

We've discussed at length the relationship between the gut and autism, and studies are now supporting that more than ever. This new study show the relationship between diabetes and the gut. And I even posted way back in 2006 a study about obesity caused by gut bacteria.

I think it's time for research money to be focused heavily on studying gut bacteria instead of other areas of health. I think there is a lot to learn there and the potential payback on those research dollars is greater than in other areas of research.

lumberjim 09-18-2014 09:38 AM

where can you get GOOD gut bacteria? that's what I want to know

Undertoad 09-18-2014 09:38 AM

i got some if you want some of mine

glatt 09-18-2014 09:48 AM

I think you feed your bacteria different foods and stop eating the foods that the bad bacteria thrive on and eat instead the foods that the good bacteria thrive on.

I don't know what those foods are, but I bet all the diets out there like Atkins and the Paleo diet and the cabbage diet, or whatever, are taking advantage of the exact same phenomenon.

We even talked a while back about drinking apple cider vinegar and how that lowers blood sugar and does other good stuff. I bet it's fucking with the bad bacteria and rewarding the good.

Clodfobble 09-18-2014 05:09 PM

The entire basis of my kids' (and now my) diet is to forbid foods that feed bad bacteria. That's the whole point. It's called the Specific Carbohydrate Diet, and while it ends up being similar to Atkins and Paleo, there are key differences because if you eat even one bite of the wrong food, you've fed the bad bacteria for several days. Paleo is good for maintaining blood sugar, and it's true you might lower the overall numbers of bad bacteria by restricting their food supply, but you will never get rid of them unless you truly starve them, which means not eating certain Paleo-legal foods like sweet potatoes or maple syrup.

What's more, many pathogenic species can go into hibernation when the food disappears, and there's a well-documented phenomenon for people on SCD where suddenly they'll get sick again for a week or two, at extremely predictable 3-month intervals. The theory is that this is the maximum length of hibernation for one or more pathogens, then they wake up and start dying in large numbers, releasing toxins that give you fatigue, diarrhea, etc. But then some of the bacteria feed on their dead buddies, and hunker down for another three months. The waves of illness get less intense each time, but people have reported the cycle going predictably for years.

There are competing theories as to whether different diseases are actually caused by different (hopefully someday identifiable) species, or whether it is simply different immune system reactions to pathogens in general. But anecdotally, remission from Crohn's on SCD tends to take 1-2 years, ulcerative colitis is usually 2-3 years, autism is 3-4. Maybe that's due to the severity of the immune response that needs correcting, or maybe it's because the specific species involved take that long to die.

There was another study recently that showed that exposure to antibiotics didn't just kill a lot of the good bacteria, it fundamentally altered the metabolism of the good bacteria that survived, and they never recovered.

Clodfobble 09-18-2014 05:13 PM

Quote:

Originally Posted by lumberjim (Post 909942)
where can you get GOOD gut bacteria? that's what I want to know

Fermented foods. Yogurt, sauerkraut, kimchi, beet kvass, pickles... Except not the pasteurized store-bought versions of any of these. Dirty hippie versions only.

Initially you get them from your mom's vaginal canal on the way out (c-section babies being at greater risk,) and then breastmilk (formula fed babies being at greater risk.) But neither of those help much if, say, your mom already has screwed up colonies.

lumberjim 09-18-2014 05:19 PM

where do you get dirty hippie yogurt? or pickles....

Clodfobble 09-18-2014 08:15 PM

Dirty hippie places like farmers' markets. Dirty hippie yogurt is very different from store yogurt, it's very thin and very sour. It's an acquired taste. But there is a brand of pickles with live cultures that is sold at most Whole Foods called Bubbie's, that tastes pretty much like you'd expect regular pickles to taste, just a tad more powerful.

Griff 09-18-2014 08:29 PM

Quote:

Originally Posted by lumberjim (Post 909942)
where can you get GOOD gut bacteria? that's what I want to know

I have dirty hippie kombucha fermenting on my kitchen counter right now.

Get The Art of Fermentation by Katz.

lumberjim 09-18-2014 08:35 PM

Quote:

Originally Posted by Clodfobble (Post 909978)
Dirty hippie places like farmers' markets. Dirty hippie yogurt is very different from store yogurt, it's very thin and very sour. It's an acquired taste. But there is a brand of pickles with live cultures that is sold at most Whole Foods called Bubbie's, that tastes pretty much like you'd expect regular pickles to taste, just a tad more powerful.

I've had Bubbies. jinx liked them.

I have a whole foods nearby too. thanks! i'm on it

Lola Bunny 09-18-2014 10:53 PM

Dirty hippie yogurt. ..that's how Vietnamese like to eat yougurt. My friend's husband like to make it and occasionally he'd give us some.

Gravdigr 09-19-2014 01:36 PM

Quote:

Originally Posted by lumberjim (Post 909942)
where can you get GOOD gut bacteria? that's what I want to know

Gut Bugs R Us?

lumberjim 09-19-2014 07:02 PM

Got the pickles. They are the yum. Also got a burrito for lunch tomorrow, a pack of chicken nibblers and a turkey wrap for today's lunch. With a drink..... $27. Not a bargain. But the burrito was a nostalgia purchase. Jinx used to make us shop there, and I would always get one. The kids got the nibblers. They have half sized carts that still cost $300 to fill. I can overload a big cart at Wegmans or shop rite for $225.

Clodfobble 09-19-2014 08:31 PM

Yeah, Whole Foods is not the place to be saving cash. Except, for some reason, on bulk cashews. We go through a lot of them, and they are $7.29 per pound at Whole Foods, compared to $10.99 per pound at my grocery store. No clue why.

Griff 09-20-2014 07:12 AM

It's not a traditional loss/leader but maybe for targeting upper-middle class households it makes sense? I guess its more likely they have a different relationship with the producers which might mean risking a poor crop at some point.

glatt 02-09-2015 10:59 AM

I just saw this news story from Friday.

In a nutshell, woman with bad C. Diff gut infection got a poop transplant from her obese daughter. It worked, killing off the C. Diff bacteria, but one year later, the woman dramatically gained weight and is now obese too.

Gravdigr 02-09-2015 03:18 PM

Dear Glatt,
If this works the other way round, would you be my transpoosion donor?

Sincerely, Gravdigr

glatt 02-09-2015 03:20 PM

I bet it does work the other way around. And when this gets widely known. I'll be rich! Rich, I tell you!

glatt 12-02-2016 11:27 AM

And now a new study published in Cell strongly links gut bacteria to Parkinsons disease.

The BBC says:
Quote:

Researchers used mice genetically programmed to develop Parkinson's as they produced very high levels of the protein alpha-synuclein, which is associated with damage in the brains of Parkinson's patients.

But only those animals with bacteria in their stomachs developed symptoms. Sterile mice remained healthy.

Further tests showed transplanting bacteria from Parkinson's patients to mice led to more symptoms than bacteria taken from healthy people.

Dr Timothy Sampson, one of the researchers at the California Institute of Technology, said: "This was the 'eureka' moment, the mice were genetically identical, the only difference was the presence or absence of gut microbiota.

"Now we were quite confident that gut bacteria regulate, and are even required for, the symptoms of Parkinson's disease."

The scientists believe the bacteria are releasing chemicals that over-activate parts of the brain, leading to damage.

footfootfoot 12-02-2016 02:11 PM

Well, this is shit news.


And speaking of dirty hippy foods, the claim of Tempeh being a great source of B-12 vitamins doesn't hold true for store bought Tempeh in the US. Our production methods are too clean and in order to develop the B-12 it needs to be dirty Asian hippy made so the B-12 producing bacteria can thrive.

orthodoc 12-02-2016 06:50 PM

You can make your own dirty hippie pickles, kimchi, etc. They are teh yum, unless you have intractable migraines that are triggered by fermented foods. :(

But for most people the homemade fermented stuff is great. And the gut microbiome is key.

glatt 09-19-2017 10:20 AM

Just saw this Scientific American article about two recent studies that found a link between gut bacteria and multiple sclerosis.

https://www.scientificamerican.com/a...ple-sclerosis/

They have a disclaimer, though: "It’s too soon to know how important the microbiome is in increasing the risk of MS compared to the 200 genetic variants that have been linked to the disease, or compared to the Epstein-Barr virus, smoking, and low levels of vitamin D, which also seem to play a role."

Clodfobble 09-19-2017 08:10 PM

I don't have the link on my phone, but MIT also just released a study confirming that a certain bacteria in the guts of pregnant mice leads to autism symptoms in their offspring. More specifically, the entire process--both the damaging of the fetal brain, and the improper activity that brain engages in after birth--is immune-modulated.

Clodfobble 04-10-2019 04:55 PM

From Science Daily:Autism Symptoms Reduced Nearly 50% Two Years After Fecal Transplant

glatt 04-10-2019 06:29 PM

Holy shit!

Griff 04-11-2019 06:36 AM

guts matter

xoxoxoBruce 04-12-2019 01:06 AM

Eat shit and live. ;)

Flint 04-12-2019 12:43 PM

Quote:

Originally Posted by xoxoxoBruce (Post 1030191)
Eat shit and live. ;)

*cram it up your ass, Bruce

xoxoxoBruce 04-13-2019 01:10 AM

That's not the way it works, this is gut bacteria is serious business, and I don't mix business with pleasure. http://cellar.org/2012/bwekk.gif

Gravdigr 04-13-2019 01:40 PM

Buttbuttbutt, whut if'n it was one o' them there anal orgies???

Group poop transplant! Anal orgies fer urrbody!

fargon 04-14-2019 04:31 PM

2 Girls 1 Cup
https://en.wikipedia.org/wiki/2_Girls_1_Cup


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