keep in mind Jag that the numbers that you look at start with M's and B's. most of us on here are looking at tens or hundreds of thousands.
i look at biotech and most other speculative items as a fun diversion. just like roullette - i don't put my serious money there. if you can't lose it you shouldn't be thinking on speculative stuff.
i'm pretty conservative by nature.(no political pun intended) i won't make even stock recommendations to my clients until they have $80-100K in well balanced mutual funds. and then only with a balanced strategy. i get clients that go against my recommendation and they buy whatever they are in love with, but usually they are out of it in 6 months and follow whatever i recommend after that.