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I'm sorry, I know some people, especially women (stereotype, yeah, but in my experience one with a basis in fact) get irrational on the subject of grandchildren. But that's just completely irrelevant.
You need to decide if this is something you want to do for this woman--considering your own health and the medical risks to you, as well as the medical condition & prospects of the donor, the likelihood of her finding another donor, and any other medical, spiritual, and ethical issues that are important to you.
Maybe the answer is yes. Maybe it's no. I couldn't make that judgement for you even if I had more information than you've posted. But this has to be between you and her. Whether she has children, or grandchildren, or ever will, or whether her daughter gets nailed by a bus crossing the street later this afternoon, is, to me, a completely irrelevant consideration.
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