07-03-2009, 08:28 AM
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#7320
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Phenomenologist
Join Date: Apr 2009
Location: Central Mississippi
Posts: 270
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Holoprosencephaly.
a cephalic disorder in which the prosencephalon (the forebrain of the embryo) fails to develop into two hemispheres. Normally, the forebrain is formed and the face begins to develop in the fifth and sixth weeks of human pregnancy. Hox genes, which guide placement of embryonic structures, fail to activate along the midline of the head, allowing structures that are normally paired on the left and right to merge. (The condition also occurs in other species, as with Cy, the Cyclops kitten.)
The most severe of the facial defects (or anomalies) is cyclopia, an abnormality characterized by the development of a single eye, located in the area normally occupied by the root of the nose, and a missing nose or a nose in the form of a proboscis (a tubular appendage) located above the eye. The condition is also referred to as cyclocephaly or synophthalmia and is very rare.
From wikipedia.
I agree, severe birth defects are very sad.
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