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Philosophy Religions, schools of thought, matters of importance and navel-gazing |
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#1 | |
To shreds, you say?
Join Date: Aug 2004
Location: in the house and on the street-how many, many feet we meet!
Posts: 18,449
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#2 |
Bioengineer and aspiring lawer
Join Date: Apr 2006
Location: Pittsburgh
Posts: 872
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Hmmm, I'll look into some stats but give me a little for numbers. The reason I mentioned men specifically is that males are more vulnerable due to the method of sex differentiation. I'll explain, but for now I'll exclude the disorders. There are four major steps in normal human sex differentiation:
1: Fertilization and determination of genetic sex 2: Formation of organs common between both sexes 3: Gonadal differentiation 4: Differentiation of the internal ducts and external genitalia The first step is the obvious one, you either get an X or a Y chromasome from your father which determines your genetic sex, either XX female or XY male. In the second, the embryo diffentiates into the cell which will become most of your organs, lungs, heart, kidneys, you get the idea. However the first stage of gonad development is also common, all embryos develop the same gonadal ridges, internal ducts, and external genitalia. Now the gonadal ridges are plainly visible at 5 weeks, and is a critical stage, if you have defects in DAX-1, SOX-9 or a number of different genes, you will not develop either testes or ovaries. By the 7th week, both male and female fetuses have both the Mullerian and Wolffian ducts, while appearing female due to the presence of urethral folds and the urogenital opening. Now, part of what Maggie was referring to occurs in the third stage, the differentiation of the gonadal ridge into either testes or ovaries. Remember how up until this point the fetus was anatomically female? At this point if the Y chromosome is present then the SRY factor will cause it to develop into testes. The female anatomy is caused by the lack of a differentiating factor, meaning that if something goes wrong at this stage the fetus automatically developes female genitalia while still being chromasomally male. The last step is similar. If testes are present then the sertoli cells will begin to produce MIS (mullerian inhibiting substance) which will halt the growth of the mullerian ducts present since the 2nd phase. In addition, androgens are now being released by the leydig cells which will cause further development of the wolffian ducts (becoming the epididymis, vas deferens, etc). The female counterparts are once again determined by the absence of these differentiating factors. Now you're probably familiar with hermaphroditism, and know that it comes in three varieties, true, male, and female. We didn't cover what causes true hermaphroditism, but the female variation is usually caused by congenital adrenal hyperplasia (adrenal glands which overproduce testosterone), and the male variation is typically androgen insensitivity syndrome which is exactly what it sounds like. That's all we covered and I can get from my textbooks, I might look up some case studies on EBSCO or the medical database, but don't hold your breath right away. I just started Christmas break, and researching this stuff in more detail than I have to know is not high on my priority list at the moment. Can anyone direct me to a good eggnog recipe? ![]()
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#3 | |
We have to go back, Kate!
Join Date: Apr 2004
Location: Yorkshire
Posts: 25,964
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#4 |
We have to go back, Kate!
Join Date: Apr 2004
Location: Yorkshire
Posts: 25,964
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I mean figures to show that the condition mainly affects men.
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#5 |
erika
Join Date: Apr 2006
Location: "the high up north"
Posts: 6,127
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So, cutting past all the bullshit and boring science talk, what you're saying, 9th, is that sex is entirely... based on... chromosomes? or physical anatomy?
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#6 |
The future is unwritten
Join Date: Oct 2002
Posts: 71,105
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Are you looking for the cocktail party answer to the meaning of life?
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The descent of man ~ Nixon, Friedman, Reagan, Trump. |
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#7 | |
Lecturer
Join Date: May 2006
Location: Atlanta
Posts: 768
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Gendered Discourse
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#8 |
The future is unwritten
Join Date: Oct 2002
Posts: 71,105
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Good point, people don't see your chromosomes, only what you present to them.
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The descent of man ~ Nixon, Friedman, Reagan, Trump. |
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#9 |
erika
Join Date: Apr 2006
Location: "the high up north"
Posts: 6,127
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I'm so confused. I identify completely as gay, but I have a girlfriend. I've got a cock. Does that mean I identify as a woman? I don't think of myself as a guy. But I don't think of myself as a girl. I resign to being treated like and calling myself a guy. But I resent it. I hate everything that being masculine, that being a guy, stands for.
I'm so tired. I have no idea what I'm talking about. Damnit, I hate being the typical whiny teenager.
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not really back, you didn't see me, i was never here shhhhhh |
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#10 | |
still says videotape
Join Date: Feb 2001
Posts: 26,813
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If you would only recognize that life is hard, things would be so much easier for you. - Louis D. Brandeis |
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#11 | |
in the Hour of Scampering
Join Date: Jan 2001
Location: Jeffersonville PA (15 mi NW of Philadelphia)
Posts: 4,060
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I giess I can speak from expereince on this...having lived in decades past and having been biologically a guy once, and biologically a woman now. The hormone balance makes a *huge* difference...and back before I transitioned I got to listen to the "you get to define your own gender role now" speech given to me more than once. Wasn't true then and I doubt it's much truer now. Being bi is all well and good. I'm bi myself. But there's a big difference between issues dealing with "who you go to bed with" and issues dealing with "who you go to bed as".
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#12 | |
lobber of scimitars
Join Date: Jul 2001
Location: Phila Burbs
Posts: 20,774
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![]() ![]() "Conspiracies are the norm, not the exception." --G. Edward Griffin The Creature from Jekyll Island High Priestess of the Church of the Whale Penis |
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#13 | |
in the Hour of Scampering
Join Date: Jan 2001
Location: Jeffersonville PA (15 mi NW of Philadelphia)
Posts: 4,060
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I'm in the same situation as a born woman post hysterectomy/oophoectomy. I suppose you could call my HRT 'mones "artificial", but they're definatey not synthetic; and it's the same Premarin millions of other women are taking. It's OK for me to take it without progesterone because cervical cancer isn't a factor. A genotype "screening test" might show me as being XY. Or might not; It's never been done and I don't know. There's any number of other possibilities.
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"Neither can his Mind be thought to be in Tune,whose words do jarre; nor his reason In frame, whose sentence is preposterous..." |
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#14 | |
The future is unwritten
Join Date: Oct 2002
Posts: 71,105
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And where did you get this information? Media portrayal? Observations? Other peoples opinions? I hesitate to bring up your age, because I'm sure you get that quite enough. But, that said, it's important in this discussion. Up to now, to get by, all you had to do was what you were told (more or less ![]() I think the honest truth is you don't fit in....except with all the other teens that are wondering the same thing you are. Don't be fooled by your peers that think they've got it all together, they just think they do...some are in for big surprises. You especially, being a military brat, have missed a continuity in your life that promotes some familiarity bred confidence. Maybe more so, because of your Dad's assignments aren't strictly military bases, but a lot of far flung civilian settings, so you don't have a lot of other military brats to commiserate with. Maybe it would be better not to try to define yourself just yet. Not before you have to, anyway. Just take it as it comes..... do and act according to what you're comfortable with.... rather than what you think you must do to reaffirm some preconceived notion of who you are. I know you are not stupid from your posts. But I am doing a lot of speculating and making judgments, about you and your life, that I have no evidence to back up. So if I'm way off base, sorry, no offense intended, just forget it. ![]() edit- While I was typing all that, griff slid in and nailed it with a lot less verbage. ![]()
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The descent of man ~ Nixon, Friedman, Reagan, Trump. Last edited by xoxoxoBruce; 12-16-2006 at 12:23 PM. |
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#15 | |
Bioengineer and aspiring lawer
Join Date: Apr 2006
Location: Pittsburgh
Posts: 872
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Quote:
![]() Ok then. I was really just throwing some information out there to clarify my comment about males being more susceptible to disorders which influence their sex phenotype, wasn't really applying it to the overarching question just yet. Let me ask this. Do you guys think we need to separate our understanding of sex and gender into two catagories? Sort of a personal and public thing to over-simplify it. It struck me that most things that we find really personal or self-defining rarely exist in the exact same form in both our private and public identities. We're making the definition of 'sex' so broad that there's no way to pin it down to something everyone can see and understand from the same angle. There's a huge biological component, no denying that, but we also want to throw in the psychological, which is what Ibram mostly refers to. Are these the same thing? Are they equally as important? Who is each important to? These aren't easy questions that we've left lodged within the bigger one, so I think we've incorrectly defined our parameters here. Perhaps a detailed look at our own definitions would help clarify a few things.
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